Yu Aida

In the heart of Italy, the Social Welfare Agency rescues young girls from hospital beds and gives them a second chance at life using the latest in cybernetic advancements. With their artificially enhanced bodies, the girls are brainwashed and trained as assassins to carry out the dirty work of the Italian Government. Despite all the modifications, they are still just children at heart, struggling for recognition from those they love, even knowing the love they feel is manufactured. (myanimelist.net)

When the Social Welfare Agency investigates the disappearance of an operative, their inquiry leads them right into the lair of their rival, the Five Republics. The assassin Triela infiltrates the hostile organization, but her search is cut short when she finds herself staring down the barrel of a gun... (myanimelist.net)