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Akbar (Mammootty) is a don in the Mangalore underworld who shares his loot with Mani Menon (Kunchan) & Uncle Sam (John Paul), 2 other prominent gangsters. Things go fine until Sam's grandson Anto (Sekhar Menon) broaches the idea of importing cheap tainted vaccines & selling them for a profit. Akbar, who was against the drug business, opposes it. Anto turns on Akbar & tries to kill him. In the attempt, Akbar gets injured badly & his wife Sana (Nyla Usha) is killed. Akbar plans revenge on Anto.
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